Olink Reveal - NGS-based proteomics

Olink Reveal — 基于NGS的新一代蛋白组学

ꂃ ꁹ

Olink Reveal——强大、简易、可及

Olink一直深耕于新一代蛋白组学领域，利用Olink专利PEA技术平台，从2016年推出商业化产品Olink Focus以来，此后每一到两年都会推出一款重要的蛋白组学新品，应用范围广泛覆盖从探索发现到靶向研究等领域，且发表文章已超过2,400多篇。新年伊始，Olink再次推出基于NGS的新一代蛋白组学新品Olink Reveal，以其“强大”、“简易”和“可及”的优势，解锁基因蛋白组学的力量，如引人注目的UKB大规模人类蛋白组研究。

在基因蛋白组学领域，尚存无限见解和未开发潜力：而基因组学和蛋白组学将是探索发现的终极合作伙伴。蛋白组学将进一步推进基因组学的成功，为人类生物学及其变化提供动态实时见解——这正是推送精准医学的关键。蛋白质在基因型和表型之间架起桥梁，并为环境做出响应。

而在将蛋白组学整合到大规模队列研究的过程中，通常会遇到多重挑战：如可选择的蛋白组Panel有限、流程复杂（对操作人员和设备要求过高）及采购新设备和样品检测成本过高。

针对以上挑战，经过4年的研发，新品Olink Reveal问世，并从三个层面都给出了解决方案：强大的蛋白库、简易的操作流程和可及的成本方案。

强大的蛋白库

Olink Reveal产品基于精心挑选的1,000多个蛋白，旨在更广泛地覆盖蛋白质组，深入剖析炎症过程，并更好的落地于疾病研究。秉承自PEA技术的高灵敏度特点，Olink Reveal检测可达fg/mL级别，并根据实际样品特点，可检测范围为86-100%。对于疾病研究相关的重要蛋白，Olink Reveal包含537个炎症/免疫反应蛋白（这些蛋白与许多疾病相关，特别是慢性病）、850多个UKB试点项目中已发现的疾病相关蛋白和700多个通过独立UKB数据被证实的与cis pQTLs相关的蛋白。

UniProt ID Gene Protein name
P09110 ACAA1 3-ketoacyl-CoA thiolase
P15309 ACP3 Prostatic acid phosphatase
O43184 ADAM12 Disintegrin and metalloproteinase domain-containing protein 12
Q86Y34 ADGRG3 Adhesion G protein-coupled receptor G3
P08319 ADH4 All-trans-retinol dehydrogenase [NAD(+)] ADH4
Q8N4X5 AFAP1L2 Actin filament-associated protein 1-like 2
P55008 AIF1 Allograft inflammatory factor 1
O43823 AKAP8 A-kinase anchor protein 8
Q9UM73 ALK ALK tyrosine kinase receptor
Q9BTT0 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E
P19801 AOC1 Amiloride-sensitive amine oxidase [copper-containing]
P27695 APEX1 DNA-(apurinic or apyrimidinic site) endonuclease
Q92974 ARHGEF2 Rho guanine nucleotide exchange factor 2
Q5T9A4 ATAD3B ATPase family AAA domain-containing protein 3B
P18846 ATF1 Cyclic AMP-dependent transcription factor ATF-1
P15336 ATF2 Cyclic AMP-dependent transcription factor ATF-2
P61421 ATP6V0D1 V-type proton ATPase subunit d 1
P56817 BACE1 Beta-secretase 1
Q9UQB8 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2
Q7Z6A9 BTLA B- and T-lymphocyte attenuator
Q6UXG8 BTNL9 Butyrophilin-like protein 9
Q49A92 C8orf34 Uncharacterized protein C8orf34
Q16566 CAMK4 Calcium/calmodulin-dependent protein kinase type IV
A8K4G0 CD300LB CMRF35-like molecule 7
P49715 CEBPA CCAAT/enhancer-binding protein alpha
Q8N2Z9 CENPS Centromere protein S
Q9UEE9 CFDP1 Craniofacial development protein 1
P11229 CHRM1 Muscarinic acetylcholine receptor M1
P20309 CHRM3 Muscarinic acetylcholine receptor M3
Q9Y4C5 CHST2 Carbohydrate sulfotransferase 2
P09496 CLTA Clathrin light chain A
P09919 CSF3 Granulocyte colony-stimulating factor
Q9NQC7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD
Q8IY21 DDX60 Probable ATP-dependent RNA helicase DDX60
Q9H2U1 DHX36 ATP-dependent DNA/RNA helicase DHX36
Q13409 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2
Q9BQ95 ECSIT Evolutionarily conserved signaling intermediate in Toll pathway
P24530 EDNRB Endothelin receptor type B
P11308 ERG Transcriptional regulator ERG
Q9UI08 EVL Ena/VASP-like protein
Q9UH90 FBXO40 F-box only protein 40
P17677 GAP43 Neuromodulin
Q9H0R5 GBP3 Guanylate-binding protein 3
P57764 GSDMD Gasdermin-D
P35367 HRH1 Histamine H1 receptor
P09914 IFIT1 Interferon-induced protein with tetratricopeptide repeats 1
P01574 IFNB1 Interferon beta
P01579 IFNG Interferon gamma
K9M1U5 IFNL4 Interferon lambda-4
Q13651 IL10RA Interleukin-10 receptor subunit alpha
Q14626 IL11RA Interleukin-11 receptor subunit alpha
Q96PD4 IL17F Interleukin-17F
Q9UHF4 IL20RA Interleukin-20 receptor subunit alpha
Q5VVH5 IRAK1BP1 Interleukin-1 receptor-associated kinase 1-binding protein 1
P06756 ITGAV Integrin alpha-V
P29376 LTK Leukocyte tyrosine kinase receptor
Q9Y5Q3 MAFB Transcription factor MafB
Q9BPZ7 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1
Q06413 MEF2C Myocyte-specific enhancer factor 2C
P25325 MPST 3-mercaptopyruvate sulfurtransferase
Q13126 MTAP S-methyl-5'-thioadenosine phosphorylase
Q12965 MYO1E Unconventional myosin-Ie
Q6ZNJ1 NBEAL2 Neurobeachin-like protein 2
A8MVU1_P14598 NCF1C_NCF1 Neutrophil cytosol factor 1/1C
O14931 NCR3 Natural cytotoxicity triggering receptor 3
O75380 NDUFS6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6
P12004 PCNA Proliferating cell nuclear antigen
Q08493 PDE4C cAMP-specific 3'
P19174 PLCG1 1-phosphatidylinositol 4
A5LHX3 PSMB11 Proteasome subunit beta type-11
Q06124 PTPN11 Tyrosine-protein phosphatase non-receptor type 11
Q15678 PTPN14 Tyrosine-protein phosphatase non-receptor type 14
O95786 RIGI Antiviral innate immune response receptor RIG-I
Q9Y572 RIPK3 Receptor-interacting serine/threonine-protein kinase 3
Q8IUD6 RNF135 E3 ubiquitin-protein ligase RNF135
Q63HN8 RNF213 E3 ubiquitin-protein ligase RNF213
P34925 RYK Tyrosine-protein kinase RYK
Q5VUM1 SDHAF4 Succinate dehydrogenase assembly factor 4
Q9BRV8 SIKE1 Suppressor of IKBKE 1
Q15796 SMAD2 Mothers against decapentaplegic homolog 2
P16150 SPN Leukosialin
Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein
Q9UEW8 STK39 STE20/SPS1-related proline-alanine-rich protein kinase
Q13148 TARDBP TAR DNA-binding protein 43
P19484 TFEB Transcription factor EB
Q8WV44 TRIM41 E3 ubiquitin-protein ligase TRIM41
Q99576 TSC22D3 TSC22 domain family protein 3
Q96LR5 UBE2E2 Ubiquitin-conjugating enzyme E2 E2
Q8IWV8 UBR2 E3 ubiquitin-protein ligase UBR2
Q9P1Q0 VPS54 Vacuolar protein sorting-associated protein 54
Q8IV63 VRK3 Inactive serine/threonine-protein kinase VRK3
A2A288 ZC3H12D Probable ribonuclease ZC3H12D
Q9Y243 AKT3 RAC-gamma serine/threonine-protein kinase
P09923 ALPI Intestinal-type alkaline phosphatase
O95260 ATE1 Arginyl-tRNA--protein transferase 1
O75787 ATP6AP2 Renin receptor
O95429 BAG4 BAG family molecular chaperone regulator 4
Q07812 BAX Apoptosis regulator BAX
Q5TBC7 BCL2L15 Bcl-2-like protein 15
P21810 BGN Biglycan
P25440 BRD2 Bromodomain-containing protein 2
P35070 BTC Probetacellulin
Q9P1Z2 CALCOCO1 Calcium-binding and coiled-coil domain-containing protein 1
P29466 CASP1 Caspase-1
P20810 CAST Calpastatin
Q13191 CBLB E3 ubiquitin-protein ligase CBL-B
P24385 CCND1 G1/S-specific cyclin-D1
P10747 CD28 T-cell-specific surface glycoprotein CD28
P40198 CEACAM3 Carcinoembryonic antigen-related cell adhesion molecule 3
P06731 CEACAM5 Carcinoembryonic antigen-related cell adhesion molecule 5
Q9UHN6 CEMIP2 Cell surface hyaluronidase
Q9UPV0 CEP164 Centrosomal protein of 164 kDa
P0CG37 CFC1 Cryptic protein
O15111 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha
Q6EIG7 CLEC6A C-type lectin domain family 6 member A
Q9BSW2 CRACR2A EF-hand calcium-binding domain-containing protein 4B
P06850 CRH Corticoliberin
P04141 CSF2 Granulocyte-macrophage colony-stimulating factor
P48730 CSNK1D Casein kinase I isoform delta
Q16619 CTF1 Cardiotrophin-1
P48061 CXCL12 Stromal cell-derived factor 1
Q9UJW0 DCTN4 Dynactin subunit 4
Q9NR30 DDX21 Nucleolar RNA helicase 2
O00148 DDX39A ATP-dependent RNA helicase DDX39A
O43583 DENR Density-regulated protein
Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L
Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1
O60573 EIF4E2 Eukaryotic translation initiation factor 4E type 2
Q8N8S7 ENAH Protein enabled homolog
Q9Y2J2 EPB41L3 Band 4.1-like protein 3
P50548 ERF ETS domain-containing transcription factor ERF
Q9NQT5 EXOSC3 Exosome complex component RRP40
Q96CS3 FAF2 FAS-associated factor 2
Q9NVF7 FBXO28 F-box only protein 28
P12319 FCER1A High affinity immunoglobulin epsilon receptor subunit alpha
Q96P31 FCRL3 Fc receptor-like protein 3
P12034 FGF5 Fibroblast growth factor 5
Q96AY3 FKBP10 Peptidyl-prolyl cis-trans isomerase FKBP10
Q5T1M5 FKBP15 FK506-binding protein 15
P36888 FLT3 Receptor-type tyrosine-protein kinase FLT3
Q04609 FOLH1 Glutamate carboxypeptidase 2
Q9UPW0 FOXJ3 Forkhead box protein J3
O43524 FOXO3 Forkhead box protein O3
P35637 FUS RNA-binding protein FUS
Q96DB9 FXYD5 FXYD domain-containing ion transport regulator 5
Q9BQS8 FYCO1 FYVE and coiled-coil domain-containing protein 1
Q14435 GALNT3 Polypeptide N-acetylgalactosaminyltransferase 3
P32456 GBP2 Guanylate-binding protein 2
P01275 GCG Pro-glucagon
P14136 GFAP Glial fibrillary acidic protein
P55789 GFER FAD-linked sulfhydryl oxidase ALR
P09211 GSTP1 Glutathione S-transferase P
Q9UQL6 HDAC5 Histone deacetylase 5
Q16665 HIF1A Hypoxia-inducible factor 1-alpha
Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0
O60760 HPGDS Hematopoietic prostaglandin D synthase
P14625 HSP90B1 Endoplasmin
Q05084 ICA1 Islet cell autoantigen 1
O14879 IFIT3 Interferon-induced protein with tetratricopeptide repeats 3
P22301 IL10 Interleukin-10
P20809 IL11 Interleukin-11
P42701 IL12RB1 Interleukin-12 receptor subunit beta-1
P35225 IL13 Interleukin-13
Q13261 IL15RA Interleukin-15 receptor subunit alpha
Q16552 IL17A Interleukin-17A
Q9P0M4 IL17C Interleukin-17C
Q8N6P7 IL22RA1 Interleukin-22 receptor subunit alpha-1
P14784 IL2RB Interleukin-2 receptor subunit beta
O76095 JTB Protein JTB
Q6UXK5 LRRN1 Leucine-rich repeat neuronal protein 1
Q7Z434 MAVS Mitochondrial antiviral-signaling protein
Q7Z6M3 MILR1 Allergin-1
Q9H3R2 MUC13 Mucin-13
Q96A32 MYL11 Myosin regulatory light chain 2
O60934 NBN Nibrin
O60260 PRKN E3 ubiquitin-protein ligase parkin
P31040 SDHA Succinate dehydrogenase [ubiquinone] flavoprotein subunit
P55735 SEC13 Protein SEC13 homolog
Q7Z698 SPRED2 Sprouty-related
P63165 SUMO1 Small ubiquitin-related modifier 1
O94941 UBOX5 RING finger protein 37
Q8IUB2 WFDC3 WAP four-disulfide core domain protein 3
Q7Z7G0 ABI3BP Target of Nesh-SH3
P00519 ABL1 Tyrosine-protein kinase ABL1
P16112 ACAN Aggrecan core protein
Q9BYF1 ACE2 Angiotensin-converting enzyme 2
P24666 ACP1 Low molecular weight phosphotyrosine protein phosphatase
Q9NPH0 ACP6 Lysophosphatidic acid phosphatase type 6
P26436 ACRV1 Acrosomal protein SP-10
P37023 ACVRL1 Serine/threonine-protein kinase receptor R3
Q96HD9 ACY3 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
P00813 ADA Adenosine deaminase
Q13444 ADAM15 Disintegrin and metalloproteinase domain-containing protein 15
Q9P0K1 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22
O75077 ADAM23 Disintegrin and metalloproteinase domain-containing protein 23
P78325 ADAM8 Disintegrin and metalloproteinase domain-containing protein 8
Q9UHI8 ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1
Q8TE58 ADAMTS15 A disintegrin and metalloproteinase with thrombospondin motifs 15
Q6UY14 ADAMTSL4 ADAMTS-like protein 4
O14514 ADGRB1 Adhesion G protein-coupled receptor B1
O60242 ADGRB3 Adhesion G protein-coupled receptor B3
Q14246 ADGRE1 Adhesion G protein-coupled receptor E1
Q9BY15 ADGRE3 Adhesion G protein-coupled receptor E3
P35318 ADM Pro-adrenomedullin
P30566 ADSL Adenylosuccinate lyase
Q8TED9 AFAP1L1 Actin filament-associated protein 1-like 1
O95994 AGR2 Anterior gradient protein 2 homolog
O00253 AGRP Agouti-related protein
Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK
Q8IVF2 AHNAK2 Protein AHNAK2
O95433 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1
Q9Y2D5 AKAP2 A-kinase anchor protein 2
Q96B36 AKT1S1 Proline-rich AKT1 substrate 1
P31751 AKT2 RAC-beta serine/threonine-protein kinase
P30838 ALDH3A1 Aldehyde dehydrogenase
Q96NU7 AMDHD1 Probable imidazolonepropionase
Q86SJ2 AMIGO2 Amphoterin-induced protein 2
Q8IV38 ANKMY2 Ankyrin repeat and MYND domain-containing protein 2
Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11
Q9UJ72 ANXA10 Annexin A10
P07355 ANXA2 Annexin A2
O00203 AP3B1 AP-3 complex subunit beta-1
Q7Z5R6 APBB1IP Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Q96GX9 APIP Methylthioribulose-1-phosphate dehydratase
P05089 ARG1 Arginase-1
Q9NZN5 ARHGEF12 Rho guanine nucleotide exchange factor 12
P07306 ASGR1 Asialoglycoprotein receptor 1
Q9BZE9 ASPSCR1 Tether containing UBX domain for GLUT4
P00966 ASS1 Argininosuccinate synthase
Q676U5 ATG16L1 Autophagy-related protein 16-1
O00244 ATOX1 Copper transport protein ATOX1
Q16864 ATP6V1F V-type proton ATPase subunit F
O75348 ATP6V1G1 V-type proton ATPase subunit G 1
O95670 ATP6V1G2 V-type proton ATPase subunit G 2
Q6UW56 ATRAID All-trans retinoic acid-induced differentiation factor
P54252 ATXN3 Ataxin-3
O15169 AXIN1 Axin-1
Q9H6S1 AZI2 5-azacytidine-induced protein 2
Q8NFL0 B3GNT7 UDP-GlcNAc:betaGal beta-1
O14867 BACH1 Transcription regulator protein BACH1
Q9UL15 BAG5 BAG family molecular chaperone regulator 5
P46379 BAG6 Large proline-rich protein BAG6
Q8NDB2 BANK1 B-cell scaffold protein with ankyrin repeats
Q96GW7 BCAN Brevican core protein
P10415 BCL2 Apoptosis regulator Bcl-2
Q07817 BCL2L1 Bcl-2-like protein 1
P11274 BCR Breakpoint cluster region protein
Q8WV28 BLNK B-cell linker protein
P12644 BMP4 Bone morphogenetic protein 4
P22004 BMP6 Bone morphogenetic protein 6
P18075 BMP7 Bone morphogenetic protein 7
O60238 BNIP3L BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Q9BWV1 BOC Brother of CDO
Q9H3K6 BOLA2_BOLA2B BolA-like protein 2
Q96DR5 BPIFA2 BPI fold-containing family A member 2
P35613 BSG Basigin
Q13410 BTN1A1 Butyrophilin subfamily 1 member A1
P78410 BTN3A2 Butyrophilin subfamily 3 member A2
Q6UX73 C16orf89 UPF0764 protein C16orf89
P02745 C1QA Complement C1q subcomponent subunit A
Q7Z5L3 C1QL2 Complement C1q-like protein 2
Q9BXI9 C1QTNF6 Complement C1q tumor necrosis factor-related protein 6
P20851 C4BPB C4b-binding protein beta chain
Q8IXQ3 C9orf40 Uncharacterized protein C9orf40
O43570 CA12 Carbonic anhydrase 12
Q9ULX7 CA14 Carbonic anhydrase 14
Q16790 CA9 Carbonic anhydrase 9
P01258 CALCA Calcitonin
P10092 CALCB Calcitonin gene-related peptide 2
Q13137 CALCOCO2 Calcium-binding and coiled-coil domain-containing protein 2
Q96GE6 CALML4 Calmodulin-like protein 4
Q5T5Y3 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1
P40121 CAPG Macrophage-capping protein
P20807 CAPN3 Calpain-3
Q13938 CAPS Calcyphosin
Q92851 CASP10 Caspase-10
P42575 CASP2 Caspase-2
P49662 CASP4 Caspase-4
P55210 CASP7 Caspase-7
Q14790 CASP8 Caspase-8
P55211 CASP9 Caspase-9
Q9NTU7 CBLN4 Cerebellin-4
P35520 CBS Cystathionine beta-synthase
Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A
Q8IX12 CCAR1 Cell division cycle and apoptosis regulator protein 1
I3L3R5 CCER2 Coiled-coil domain-containing glutamate-rich protein 2
P06307 CCK Cholecystokinin
P51671 CCL11 Eotaxin
P78556 CCL20 C-C motif chemokine 20
O15444 CCL25 C-C motif chemokine 25
Q9Y258 CCL26 C-C motif chemokine 26
Q9NRJ3 CCL28 C-C motif chemokine 28
P10147 CCL3 C-C motif chemokine 3
P13236 CCL4 C-C motif chemokine 4
P80098 CCL7 C-C motif chemokine 7
P80075 CCL8 C-C motif chemokine 8
O00622 CCN1 CCN family member 1
O95388 CCN4 CCN family member 4
Q93033 CD101 Immunoglobulin superfamily member 2
O95971 CD160 CD160 antigen
P41217 CD200 OX-2 membrane glycoprotein
Q8TD46 CD200R1 Cell surface glycoprotein CD200 receptor 1
Q9UJ71 CD207 C-type lectin domain family 4 member K
P20273 CD22 B-cell receptor CD22
Q15762 CD226 CD226 antigen
Q9BZW8 CD244 Natural killer cell receptor 2B4
Q9NZQ7 CD274 Programmed cell death 1 ligand 1
Q496F6 CD300E CMRF35-like molecule 2
Q8IX05 CD302 CD302 antigen
P28907 CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
P01730 CD4 T-cell surface glycoprotein CD4
P29965 CD40LG CD40 ligand
P06127 CD5 T-cell surface glycoprotein CD5
P30203 CD6 T-cell differentiation antigen CD6
P08962 CD63 CD63 antigen
P09564 CD7 T-cell antigen CD7
P32970 CD70 CD70 antigen
P40259 CD79B B-cell antigen receptor complex-associated protein beta chain
Q01151 CD83 CD83 antigen
Q9UIB8 CD84 SLAM family member 5
P42081 CD86 T-lymphocyte activation antigen CD86
Q8NHZ8 CDC26 Anaphase-promoting complex subunit CDC26
Q9H5V8 CDCP1 CUB domain-containing protein 1
P22223 CDH3 Cadherin-3
P38936 CDKN1A Cyclin-dependent kinase inhibitor 1
Q49AH0 CDNF Cerebral dopamine neurotrophic factor
Q15517 CDSN Corneodesmosin
Q2WEN9 CEACAM16 Carcinoembryonic antigen-related cell adhesion molecule 16
Q7Z692 CEACAM19 Carcinoembryonic antigen-related cell adhesion molecule 19
Q3KPI0 CEACAM21 Carcinoembryonic antigen-related cell adhesion molecule 21
P31997 CEACAM8 Carcinoembryonic antigen-related cell adhesion molecule 8
P17676 CEBPB CCAAT/enhancer-binding protein beta
O00748 CES2 Cocaine esterase
Q6UWW8 CES3 Carboxylesterase 3
Q96G28 CFAP36 Cilia- and flagella-associated protein 36
Q9BRQ6 CHCHD6 MICOS complex subunit MIC25
Q07065 CKAP4 Cytoskeleton-associated protein 4
Q8IUN9 CLEC10A C-type lectin domain family 10 member A
Q5QGZ9 CLEC12A C-type lectin domain family 12 member A
Q8NC01 CLEC1A C-type lectin domain family 1 member A
Q9UMR7 CLEC4A C-type lectin domain family 4 member A
Q8WTT0 CLEC4C C-type lectin domain family 4 member C
Q8WXI8 CLEC4D C-type lectin domain family 4 member D
Q6UXB4 CLEC4G C-type lectin domain family 4 member G
Q9NY25 CLEC5A C-type lectin domain family 5 member A
Q9BXN2 CLEC7A C-type lectin domain family 7 member A
Q9H4D0 CLSTN2 Calsyntenin-2
Q9BQT9 CLSTN3 Calsyntenin-3
P09543 CNP 2'
Q8N129 CNPY4 Protein canopy homolog 4
Q02246 CNTN2 Contactin-2
Q9UHC6 CNTNAP2 Contactin-associated protein-like 2
Q17RW2 COL24A1 Collagen alpha-1(XXIV) chain
Q2UY09 COL28A1 Collagen alpha-1(XXVIII) chain
P20849 COL9A1 Collagen alpha-1(IX) chain
Q9P000 COMMD9 COMM domain-containing protein 9
P21964 COMT Catechol O-methyltransferase
P16870 CPE Carboxypeptidase E
Q9H3G5 CPVL Probable serine carboxypeptidase CPVL
P78560 CRADD Death domain-containing protein CRADD
P16562 CRISP2 Cysteine-rich secretory protein 2
Q9UBG3 CRNN Cornulin
O95727 CRTAM Cytotoxic and regulatory T-cell molecule
O95825 CRYZL1 Quinone oxidoreductase-like protein 1
P09603 CSF1 Macrophage colony-stimulating factor 1
P32927 CSF2RB Cytokine receptor common subunit beta
Q99062 CSF3R Granulocyte colony-stimulating factor receptor
P50461 CSRP3 Cysteine and glycine-rich protein 3
P28325 CST5 Cystatin-D
P32929 CTH Cystathionine gamma-lyase
P40313 CTRL Chymotrypsin-like protease CTRL-1
Q9UBX1 CTSF Cathepsin F
P09668 CTSH Pro-cathepsin H
P43234 CTSO Cathepsin O
O60911 CTSV Cathepsin L2
P78423 CX3CL1 Fractalkine
P78310 CXADR Coxsackievirus and adenovirus receptor
P09341 CXCL1 Growth-regulated alpha protein
P02778 CXCL10 C-X-C motif chemokine 10
Q6UXB2 CXCL17 C-X-C motif chemokine 17
P80162 CXCL6 C-X-C motif chemokine 6
P10145 CXCL8 Interleukin-8
Q07325 CXCL9 C-X-C motif chemokine 9
Q6BCY4 CYB5R2 NADH-cytochrome b5 reductase 2
Q9UIK4 DAPK2 Death-associated protein kinase 2
Q9UN19 DAPP1 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
Q16643 DBN1 Drebrin
P07585 DCN Decorin
Q96C86 DCPS m7GpppX diphosphatase
Q14203 DCTN1 Dynactin subunit 1
Q13561 DCTN2 Dynactin subunit 2
Q16698 DECR1 2
P81534 DEFB103A_DEFB103B Beta-defensin 103
O00273 DFFA DNA fragmentation factor subunit alpha
P23743 DGKA Diacylglycerol kinase alpha
P49366 DHPS Deoxyhypusine synthase
Q9UBT3 DKK4 Dickkopf-related protein 4
P78352 DLG4 Disks large homolog 4
Q8WW22 DNAJA4 DnaJ homolog subfamily A member 4
P25685 DNAJB1 DnaJ homolog subfamily B member 1
O75061 DNAJC6 Putative tyrosine-protein phosphatase auxilin
Q05193 DNM1 Dynamin-1
Q9UQ16 DNM3 Dynamin-3
Q6XZF7 DNMBP Dynamin-binding protein
Q9ULA0 DNPEP Aspartyl aminopeptidase
P16444 DPEP1 Dipeptidase 1
Q9H4A9 DPEP2 Dipeptidase 2
Q8N608 DPP10 Inactive dipeptidyl peptidase 10
P42658 DPP6 Dipeptidyl aminopeptidase-like protein 6
Q9C005 DPY30 Protein dpy-30 homolog
Q8NBI3 DRAXIN Draxin
P32926 DSG3 Desmoglein-3
O60941 DTNB Dystrobrevin beta
Q8N9I9 DTX3 Probable E3 ubiquitin-protein ligase DTX3
P33316 DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase
O00559 EBAG9 Receptor-binding cancer antigen expressed on SiSo cells
Q14213_Q8NEV9 EBI3_IL27 Interleukin-27
P42892 ECE1 Endothelin-converting enzyme 1
Q9HAV5 EDA2R Tumor necrosis factor receptor superfamily member 27
Q9UNE0 EDAR Tumor necrosis factor receptor superfamily member EDAR
Q96C19 EFHD2 EF-hand domain-containing protein D2
P52798 EFNA4 Ephrin-A4
Q63HQ2 EGFLAM Pikachurin
Q9GZT9 EGLN1 Egl nine homolog 1
Q9H223 EHD4 EH domain-containing protein 4
P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2
P06730 EIF4E Eukaryotic translation initiation factor 4E
Q15370 ELOB Elongin-B
Q9HC35 EML4 Echinoderm microtubule-associated protein-like 4
P21128 ENDOU Poly(U)-specific endoribonuclease
P22413 ENPP1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Q6UWR7 ENPP6 Glycerophosphocholine cholinephosphodiesterase ENPP6
O75356 ENTPD5 Ectonucleoside triphosphate diphosphohydrolase 5
O75354 ENTPD6 Ectonucleoside triphosphate diphosphohydrolase 6
P29317 EPHA2 Ephrin type-A receptor 2
O15197 EPHB6 Ephrin type-B receptor 6
Q9H6S3 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2
Q15303 ERBB4 Receptor tyrosine-protein kinase erbB-4
O14944 EREG Proepiregulin
O75460 ERN1 Serine/threonine-protein kinase/endoribonuclease IRE1
Q9BS26 ERP44 Endoplasmic reticulum resident protein 44
P03372 ESR1 Estrogen receptor
P58658 EVA1C Protein eva-1 homolog C
O60447 EVI5 Ecotropic viral integration site 5 protein homolog
P15311 EZR Ezrin
P13726 F3 Tissue factor
P58499 FAM3B Protein FAM3B
Q96BQ1 FAM3D Protein FAM3D
P48023 FASLG Tumor necrosis factor ligand superfamily member 6
P24071 FCAR Immunoglobulin alpha Fc receptor
Q96LA5 FCRL2 Fc receptor-like protein 2
Q6DN72 FCRL6 Fc receptor-like protein 6
O95750 FGF19 Fibroblast growth factor 19
P09038 FGF2 Fibroblast growth factor 2
Q9NSA1 FGF21 Fibroblast growth factor 21
Q9GZV9 FGF23 Fibroblast growth factor 23
Q8TAT2 FGFBP3 Fibroblast growth factor-binding protein 3
P09769 FGR Tyrosine-protein kinase Fgr
P49789 FHIT Bis(5'-adenosyl)-triphosphatase
Q02790 FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4
Q13451 FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5
Q9UIM3 FKBPL FK506-binding protein-like
O43155 FLRT2 Leucine-rich repeat transmembrane protein FLRT2
P49771 FLT3LG Fms-related tyrosine kinase 3 ligand
O95466 FMNL1 Formin-like protein 1
Q4ZHG4 FNDC1 Fibronectin type III domain-containing protein 1
P49354 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Q12778 FOXO1 Forkhead box protein O1
Q92765 FRZB Secreted frizzled-related protein 3
Q12841 FSTL1 Follistatin-related protein 1
P09958 FURIN Furin
Q9BYC5 FUT8 Alpha-(1
Q86SR1 GALNT10 Polypeptide N-acetylgalactosaminyltransferase 10
Q10471 GALNT2 Polypeptide N-acetylgalactosaminyltransferase 2
P04062 GBA1 Lysosomal acid glucosylceramidase
Q02742 GCNT1 Beta-1
P39905 GDNF Glial cell line-derived neurotrophic factor
P56159 GFRA1 GDNF family receptor alpha-1
O00451 GFRA2 GDNF family receptor alpha-2
O60609 GFRA3 GDNF family receptor alpha-3
Q6UXV0 GFRAL GDNF family receptor alpha-like
Q9Y2X7 GIT1 ARF GTPase-activating protein GIT1
P48060 GLIPR1 Glioma pathogenesis-related protein 1
Q9NS18 GLRX2 Glutaredoxin-2
P36959 GMPR GMP reductase 1
Q9HD26 GOPC Golgi-associated PDZ and coiled-coil motif-containing protein
P55259 GP2 Pancreatic secretory granule membrane major glycoprotein GP2
Q99795 GPA33 Cell surface A33 antigen
P35052 GPC1 Glypican-1
P78333 GPC5 Glypican-5
P21695 GPD1 Glycerol-3-phosphate dehydrogenase [NAD(+)]
Q8IV16 GPIHBP1 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
Q6UWK7 GPR15LG Protein GPR15L
O15354 GPR37 Prosaposin receptor GPR37
P07492 GRP Gastrin-releasing peptide
Q9HAV7 GRPEL1 GrpE protein homolog 1
P12544 GZMA Granzyme A
P10144 GZMB Granzyme B
P20718 GZMH Granzyme H
Q9UJM8 HAO1 Hydroxyacid oxidase 1
Q96D42 HAVCR1 Hepatitis A virus cellular receptor 1
Q99075 HBEGF Proheparin-binding EGF-like growth factor
P14317 HCLS1 Hematopoietic lineage cell-specific protein
Q9UKV0 HDAC9 Histone deacetylase 9
Q9BQS7 HEPH Hephaestin
P14210 HGF Hepatocyte growth factor
Q03014 HHEX Hematopoietically-expressed homeobox protein HHEX
P04439 HLA-A HLA class I histocompatibility antigen
P08397 HMBS Porphobilinogen deaminase
P30519 HMOX2 Heme oxygenase 2
P50135 HNMT Histamine N-methyltransferase
Q9BUJ2 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1
Q9NSC5 HOMER3 Homer protein homolog 3
P01112 HRAS GTPase HRas
P23327 HRC Sarcoplasmic reticulum histidine-rich calcium-binding protein
Q96MM7 HS6ST2 Heparan-sulfate 6-O-sulfotransferase 2
P28845 HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1
P48723 HSPA13 Heat shock 70 kDa protein 13
O14558 HSPB6 Heat shock protein beta-6
Q14773 ICAM4 Intercellular adhesion molecule 4
O75144 ICOSLG ICOS ligand
P14902 IDO1 Indoleamine 2
P22304 IDS Iduronate 2-sulfatase
P35475 IDUA Alpha-L-iduronidase
P13284 IFI30 Gamma-interferon-inducible lysosomal thiol reductase
P17181 IFNAR1 Interferon alpha/beta receptor 1
P15260 IFNGR1 Interferon gamma receptor 1
P38484 IFNGR2 Interferon gamma receptor 2
Q8IU57 IFNLR1 Interferon lambda receptor 1
P78318 IGBP1 Immunoglobulin-binding protein 1
P08069 IGF1R Insulin-like growth factor 1 receptor
Q6B9Z1 IGFL4 Insulin growth factor-like family member 4
O75054 IGSF3 Immunoglobulin superfamily member 3
Q9Y6K9 IKBKG NF-kappa-B essential modulator
P29459_P29460 IL12A_IL12B Interleukin-12
P29460 IL12B Interleukin-12 subunit beta
P40933 IL15 Interleukin-15
Q14005 IL16 Pro-interleukin-16
Q8TAD2 IL17D Interleukin-17D
Q9NRM6 IL17RB Interleukin-17 receptor B
Q13478 IL18R1 Interleukin-18 receptor 1
O95256 IL18RAP Interleukin-18 receptor accessory protein
P01583 IL1A Interleukin-1 alpha
P01584 IL1B Interleukin-1 beta
Q9HB29 IL1RL2 Interleukin-1 receptor-like 2
P60568 IL2 Interleukin-2
Q9NYY1 IL20 Interleukin-20
Q9GZX6 IL22 Interleukin-22
Q5VWK5 IL23R Interleukin-23 receptor
Q8NI17 IL31RA Interleukin-31 receptor subunit alpha
P24001 IL32 Interleukin-32
O95760 IL33 Interleukin-33
Q9NZH7 IL36B Interleukin-36 beta
Q9NZH8 IL36G Interleukin-36 gamma
P26951 IL3RA Interleukin-3 receptor subunit alpha
P05112 IL4 Interleukin-4
P24394 IL4R Interleukin-4 receptor subunit alpha
Q01344 IL5RA Interleukin-5 receptor subunit alpha
P05231 IL6 Interleukin-6
P13232 IL7 Interleukin-7
P15248 IL9 Interleukin-9
P29218 IMPA1 Inositol monophosphatase 1
P49441 INPP1 Inositol polyphosphate 1-phosphatase
Q92835 INPP5D Phosphatidylinositol 3
O15357 INPPL1 Phosphatidylinositol 3
Q9Y5Q6 INSL5 Insulin-like peptide INSL5
Q8WWN9 IPCEF1 Interactor protein for cytohesin exchange factors 1
Q13576 IQGAP2 Ras GTPase-activating-like protein IQGAP2
Q12912 IRAG2 Inositol 1
P51617 IRAK1 Interleukin-1 receptor-associated kinase 1
Q9NWZ3 IRAK4 Interleukin-1 receptor-associated kinase 4
B1AKI9 ISM1 Isthmin-1
Q96J02 ITCH E3 ubiquitin-protein ligase Itchy homolog
Q9UKX5 ITGA11 Integrin alpha-11
P20701 ITGAL Integrin alpha-L
Q9UKP3 ITGB1BP2 Integrin beta-1-binding protein 2
P18564 ITGB6 Integrin beta-6
P26010 ITGB7 Integrin beta-7
O43736 ITM2A Integral membrane protein 2A
Q14643 ITPR1 Inositol 1
P23276 KEL Kell blood group glycoprotein
P50053 KHK Ketohexokinase
Q5VV43 KIAA0319 Dyslexia-associated protein KIAA0319
Q8IZA0 KIAA0319L Dyslexia-associated protein KIAA0319-like protein
Q14807 KIF22 Kinesin-like protein KIF22
O95239 KIF4A Chromosome-associated kinesin KIF4A
Q92845 KIFAP3 Kinesin-associated protein 3
P43627_P43628 KIR2DL2_KIR2DL3 Killer cell immunoglobulin-like receptor 2DL2
P43629 KIR3DL1 Killer cell immunoglobulin-like receptor 3DL1
P21583 KITLG Kit ligand
Q86Z14 KLB Beta-klotho
O60662 KLHL41 Kelch-like protein 41
Q9UKR3 KLK13 Kallikrein-13
Q9H2R5 KLK15 Kallikrein-15
Q12918 KLRB1 Killer cell lectin-like receptor subfamily B member 1
Q13241 KLRD1 Natural killer cells antigen CD94
Q9NZS2 KLRF1 Killer cell lectin-like receptor subfamily F member 1
P26718 KLRK1 NKG2-D type II integral membrane protein
P08727 KRT19 Keratin
P13647 KRT5 Keratin
Q16773 KYAT1 Kynurenine--oxoglutarate transaminase 1
Q16719 KYNU Kynureninase
P32004 L1CAM Neural cell adhesion molecule L1
P18627 LAG3 Lymphocyte activation gene 3 protein
Q6ISS4 LAIR2 Leukocyte-associated immunoglobulin-like receptor 2
P07942 LAMB1 Laminin subunit beta-1
Q9UQV4 LAMP3 Lysosome-associated membrane glycoprotein 3
O43561 LAT Linker for activation of T-cells family member 1
Q9GZY6 LAT2 Linker for activation of T-cells family member 2
O95835 LATS1 Serine/threonine-protein kinase LATS1
Q6UX15 LAYN Layilin
P06239 LCK Tyrosine-protein kinase Lck
Q6UWW0 LCN15 Lipocalin-15
O00292 LEFTY2 Left-right determination factor 2
P47929 LGALS7_LGALS7B Galectin-7
P15018 LIF Leukemia inhibitory factor
P42702 LIFR Leukemia inhibitory factor receptor
Q8NHJ6 LILRB4 Leukocyte immunoglobulin-like receptor subfamily B member 4
P07098 LIPF Gastric triacylglycerol lipase
P20700 LMNB1 Lamin-B1
Q03252 LMNB2 Lamin-B2
P29536 LMOD1 Leiomodin-1
P22079 LPO Lactoperoxidase
O75427 LRCH4 Leucine-rich repeat and calponin homology domain-containing protein 4
Q96JA1 LRIG1 Leucine-rich repeats and immunoglobulin-like domains protein 1
Q8N386 LRRC25 Leucine-rich repeat-containing protein 25
A6NM11 LRRC37A2 Leucine-rich repeat-containing protein 37A2
Q32MZ4 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1
P09960 LTA4H Leukotriene A-4 hydrolase
Q9NS15 LTBP3 Latent-transforming growth factor beta-binding protein 3
Q86TE4 LUZP2 Leucine zipper protein 2
Q9BS40 LXN Latexin
O60449 LY75 Lymphocyte antigen 75
Q9HBG7 LY9 T-lymphocyte surface antigen Ly-9
Q9Y6Y9 LY96 Lymphocyte antigen 96
Q9Y6D9 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1
P20916 MAG Myelin-associated glycoprotein
O60476 MAN1A2 Mannosyl-oligosaccharide 1
Q02750 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1
P52564 MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6
Q99683 MAP3K5 Mitogen-activated protein kinase kinase kinase 5
Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5
P45984 MAPK9 Mitogen-activated protein kinase 9
P49137 MAPKAPK2 MAP kinase-activated protein kinase 2
P10636 MAPT Microtubule-associated protein tau
P48740 MASP1 Mannan-binding lectin serine protease 1
O15232 MATN3 Matrilin-3
O15068 MCF2L Guanine nucleotide exchange factor DBS
Q8NFP4 MDGA1 MAM domain-containing glycosylphosphatidylinositol anchor protein 1
Q9BV79 MECR Enoyl-[acyl-carrier-protein] reductase
P08582 MELTF Melanotransferrin
Q16819 MEP1A Meprin A subunit alpha
Q6UB28 METAP1D Methionine aminopeptidase 1D
P50579 METAP2 Methionine aminopeptidase 2
Q29980_Q29983 MICA_MICB MHC class I polypeptide-related sequence A and MHC class I polypeptide-related sequence B
Q8NBR6 MINDY2 Ubiquitin carboxyl-terminal hydrolase MINDY-2
P46013 MKI67 Proliferation marker protein Ki-67
Q9BUB5 MKNK1 MAP kinase-interacting serine/threonine-protein kinase 1
P12872 MLN Promotilin
P08473 MME Neprilysin
P09238 MMP10 Stromelysin-2
P39900 MMP12 Macrophage metalloelastase
P45452 MMP13 Collagenase 3
Q16653 MOG Myelin-oligodendrocyte glycoprotein
Q14149 MORC3 MORC family CW-type zinc finger protein 3
Q5T2T1 MPP7 MAGUK p55 subfamily member 7
P11836 MS4A1 B-lymphocyte antigen CD20
Q13421 MSLN Mesothelin
O14793 MSTN Growth/differentiation factor 8
Q86UE4 MTDH Protein LYRIC
Q8WXI7 MUC16 Mucin-16
Q8N307 MUC20 Mucin-20
Q03426 MVK Mevalonate kinase
P08590 MYL3 Myosin light chain 3
Q13459 MYO9B Unconventional myosin-IXb
Q02083 NAAA N-acylethanolamine-hydrolyzing acid amidase
Q96RE7 NACC1 Nucleus accumbens-associated protein 1
P17050 NAGA Alpha-N-acetylgalactosaminidase
Q9UJ70 NAGK N-acetyl-D-glucosamine kinase
Q6XQN6 NAPRT Nicotinate phosphoribosyltransferase
O14594 NCAN Neurocan core protein
Q9NZQ3 NCKIPSD NCK-interacting protein with SH3 domain
O76036 NCR1 Natural cytotoxicity triggering receptor 1
Q68D85 NCR3LG1 Natural cytotoxicity triggering receptor 3 ligand 1
P62166 NCS1 Neuronal calcium sensor 1
Q92597 NDRG1 Protein NDRG1
Q16718 NDUFA5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Q8N183 NDUFAF2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2
P17568 NDUFB7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Q7Z6G3 NECAB2 N-terminal EF-hand calcium-binding protein 2
P07196 NEFL Neurofilament light polypeptide
Q92832 NELL1 Protein kinase C-binding protein NELL1
Q92859 NEO1 Neogenin
O94916 NFAT5 Nuclear factor of activated T-cells 5
O95644 NFATC1 Nuclear factor of activated T-cells
Q12968 NFATC3 Nuclear factor of activated T-cells
P19838 NFKB1 Nuclear factor NF-kappa-B p105 subunit
O00221 NFKBIE NF-kappa-B inhibitor epsilon
Q9UMS0 NFU1 NFU1 iron-sulfur cluster scaffold homolog
Q12986 NFX1 Transcriptional repressor NF-X1
Q9H9Q4 NHEJ1 Non-homologous end-joining factor 1
Q86X76 NIT1 Deaminated glutathione amidase
Q8N2Q7 NLGN1 Neuroligin-1
Q13287 NMI N-myc-interactor
P29475 NOS1 Nitric oxide synthase
P35228 NOS2 Nitric oxide synthase
P29474 NOS3 Nitric oxide synthase
O60500 NPHS1 Nephrin
P06748 NPM1 Nucleophosmin
P23582 NPPC C-type natriuretic peptide
O95502 NPTXR Neuronal pentraxin receptor
P01303 NPY Pro-neuropeptide Y
P15559 NQO1 NAD(P)H dehydrogenase [quinone] 1
Q99748 NRTN Neurturin
Q9BXI3 NT5C1A Cytosolic 5'-nucleotidase 1A
P20783 NTF3 Neurotrophin-3
Q9Y5A7 NUB1 NEDD8 ultimate buster 1
P80303 NUCB2 Nucleobindin-2
Q9Y266 NUDC Nuclear migration protein nudC
Q8IVD9 NUDCD3 NudC domain-containing protein 3
P49757 NUMB Protein numb homolog
Q9UKX7 NUP50 Nuclear pore complex protein Nup50
O95157 NXPH3 Neurexophilin-3
Q9NPH6 OBP2B Odorant-binding protein 2b
Q16625 OCLN Occludin
A1E959 ODAM Odontogenic ameloblast-associated protein
O60502 OGA Protein O-GlcNAcase
Q9NZT2 OGFR Opioid growth factor receptor
P13725 OSM Oncostatin-M
Q6GQQ9 OTUD7B OTU domain-containing protein 7B
Q9Y2J8 PADI2 Protein-arginine deiminase type-2
Q9UM07 PADI4 Protein-arginine deiminase type-4
P09466 PAEP Glycodelin
Q9NWQ8 PAG1 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
O75781 PALM Paralemmin-1
Q8IXS6 PALM2 Paralemmin-2
Q13219 PAPPA Pappalysin-1
P09874 PARP1 Poly [ADP-ribose] polymerase 1
Q96AQ6 PBXIP1 Pre-B-cell leukemia transcription factor-interacting protein 1
Q15366 PCBP2 Poly(rC)-binding protein 2
Q9NPG4 PCDH12 Protocadherin-12
O60245 PCDH7 Protocadherin-7
Q9HC56 PCDH9 Protocadherin-9
Q9Y5E8 PCDHB15 Protocadherin beta-15
Q16549 PCSK7 Proprotein convertase subtilisin/kexin type 7
Q15116 PDCD1 Programmed cell death protein 1
Q9BQ51 PDCD1LG2 Programmed cell death 1 ligand 2
Q9NRA1 PDGFC Platelet-derived growth factor C
Q5T2W1 PDZK1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3
P56645 PER3 Period circadian protein homolog 3
O60825 PFKFB2 6-phosphofructo-2-kinase/fructose-2
P49763 PGF Placenta growth factor
Q96LB9 PGLYRP3 Peptidoglycan recognition protein 3
Q96G03 PGM2 Phosphoglucomutase-2
P06401 PGR Progesterone receptor
Q86UU1 PHLDB1 Pleckstrin homology-like domain family B member 1
Q6ZUJ8 PIK3AP1 Phosphoinositide 3-kinase adapter protein 1
Q9Y2I7 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase
O43164 PJA2 E3 ubiquitin-protein ligase Praja-2
Q13563 PKD2 Polycystin-2
O15496 PLA2G10 Group 10 secretory phospholipase A2
O60240 PLIN1 Perilipin-1
Q9HCM2 PLXNA4 Plexin-A4
P54315 PNLIPRP1 Inactive pancreatic lipase-related protein 1
Q8ND90 PNMA1 Paraneoplastic antigen Ma1
Q8TCS8 PNPT1 Polyribonucleotide nucleotidyltransferase 1
Q8WVV4 POF1B Protein POF1B
P61218 POLR2F DNA-directed RNA polymerases I
Q9H1D9 POLR3F DNA-directed RNA polymerase III subunit RPC6
P01189 POMC Pro-opiomelanocortin
Q15165 PON2 Serum paraoxonase/arylesterase 2
Q9UNP9 PPIE Peptidyl-prolyl cis-trans isomerase E
O60437 PPL Periplakin
Q9Y570 PPME1 Protein phosphatase methylesterase 1
Q15172 PPP2R5A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Q06830 PRDX1 Peroxiredoxin-1
P30041 PRDX6 Peroxiredoxin-6
Q9HCU5 PREB Prolactin regulatory element-binding protein
P51888 PRELP Prolargin
Q9Y478 PRKAB1 5'-AMP-activated protein kinase subunit beta-1
P31321 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit
P13861 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit
O75569 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A
P58294 PROK1 Prokineticin-1
Q96M27 PRRC1 Protein PRRC1
Q5FWE3 PRRT3 Proline-rich transmembrane protein 3
Q2VWP7 PRTG Protogenin
Q6NUJ1 PSAPL1 Proactivator polypeptide-like 1
O75475 PSIP1 PC4 and SFRS1-interacting protein
Q99460 PSMD1 26S proteasome non-ATPase regulatory subunit 1
Q16401 PSMD5 26S proteasome non-ATPase regulatory subunit 5
O00233 PSMD9 26S proteasome non-ATPase regulatory subunit 9
Q06323 PSME1 Proteasome activator complex subunit 1
Q9UL46 PSME2 Proteasome activator complex subunit 2
Q9BT73 PSMG3 Proteasome assembly chaperone 3
Q5JS54 PSMG4 Proteasome assembly chaperone 4
O60542 PSPN Persephin
O43586 PSTPIP1 Proline-serine-threonine phosphatase-interacting protein 1
P60484 PTEN Phosphatidylinositol 3
Q9H7Z7 PTGES2 Prostaglandin E synthase 2
P01270 PTH Parathyroid hormone
Q03431 PTH1R Parathyroid hormone/parathyroid hormone-related peptide receptor
Q13308 PTK7 Inactive tyrosine-protein kinase 7
O75365 PTP4A3 Protein tyrosine phosphatase type IVA 3
P18031 PTPN1 Tyrosine-protein phosphatase non-receptor type 1
P23467 PTPRB Receptor-type tyrosine-protein phosphatase beta
Q15262 PTPRK Receptor-type tyrosine-protein phosphatase kappa
Q92932 PTPRN2 Receptor-type tyrosine-protein phosphatase N2
Q15256 PTPRR Receptor-type tyrosine-protein phosphatase R
P23471 PTPRZ1 Receptor-type tyrosine-protein phosphatase zeta
P49023 PXN Paxillin
Q8WXC3 PYDC1 Pyrin domain-containing protein 1
Q6K0P9 PYHIN1 Pyrin and HIN domain-containing protein 1
Q8WUD1 RAB2B Ras-related protein Rab-2B
Q96AX2 RAB37 Ras-related protein Rab-37
Q8TBN0 RAB3IL1 Guanine nucleotide exchange factor for Rab-3A
Q7Z6P3 RAB44 Ras-related protein Rab-44
Q5R372 RABGAP1L Rab GTPase-activating protein 1-like
Q5VY80_Q9BZM5 RAET1L_ULBP2 UL16-binding protein 2
P11234 RALB Ras-related protein Ral-B
O60895 RAMP2 Receptor activity-modifying protein 2
P49792 RANBP2 E3 SUMO-protein ligase RanBP2
P47736 RAP1GAP Rap1 GTPase-activating protein 1
Q7LDG7 RASGRP2 RAS guanyl-releasing protein 2
A6NFN3 RBFOX3 RNA binding protein fox-1 homolog 3
Q9H477 RBKS Ribokinase
Q93062 RBPMS RNA-binding protein with multiple splicing
Q5TC82 RC3H1 Roquin-1
O95980 RECK Reversion-inducing cysteine-rich protein with Kazal motifs
Q6UW15 REG3G Regenerating islet-derived protein 3-gamma
P07949 RET Proto-oncogene tyrosine-protein kinase receptor Ret
P35249 RFC4 Replication factor C subunit 4
Q9H4X1 RGCC Regulator of cell cycle RGCC
P57771 RGS8 Regulator of G-protein signaling 8
Q96NA2 RILP Rab-interacting lysosomal protein
Q8NC42 RNF149 E3 ubiquitin-protein ligase RNF149
Q96BH1 RNF25 E3 ubiquitin-protein ligase RNF25
Q9H4P4 RNF41 E3 ubiquitin-protein ligase NRDP1
Q9HCK4 ROBO2 Roundabout homolog 2
Q9Y2J0 RPH3A Rabphilin-3A
P50914 RPL14 60S ribosomal protein L14
Q2MKA7 RSPO1 R-spondin-1
Q9BXY4 RSPO3 R-spondin-3
Q9BSG5 RTBDN Retbindin
Q9BZR6 RTN4R Reticulon-4 receptor
P31949 S100A11 Protein S100-A11
P80511 S100A12 Protein S100-A12
Q99584 S100A13 Protein S100-A13
Q96FQ6 S100A16 Protein S100-A16
Q8IVG5 SAMD9L Sterile alpha motif domain-containing protein 9-like
O75995 SASH3 SAM and SH3 domain-containing protein 3
Q9H4B6 SAV1 Protein salvador homolog 1
O14828 SCAMP3 Secretory carrier-associated membrane protein 3
Q8WTV0 SCARB1 Scavenger receptor class B member 1
Q14108 SCARB2 Lysosome membrane protein 2
P13521 SCG2 Secretogranin-2
O76038 SCGN Secretagogin
Q8IWT1 SCN4B Sodium channel subunit beta-4
Q9HB40 SCPEP1 Retinoid-inducible serine carboxypeptidase
Q14160 SCRIB Protein scribble homolog
Q12765 SCRN1 Secernin-1
P21912 SDHB Succinate dehydrogenase [ubiquinone] iron-sulfur subunit
Q9UBV2 SEL1L Protein sel-1 homolog 1
Q92599 SEPTIN8 Septin-8
P48594 SERPINB4 Serpin B4
P36952 SERPINB5 Serpin B5
P50452 SERPINB8 Serpin B8
P50453 SERPINB9 Serpin B9
O75830 SERPINI2 Serpin I2
Q53H47 SETMAR Histone-lysine N-methyltransferase SETMAR
Q53EL9 SEZ6 Seizure protein 6 homolog
Q6UXD5 SEZ6L2 Seizure 6-like protein 2
Q8IWL1 SFTPA2 Pulmonary surfactant-associated protein A2
Q9UQQ2 SH2B3 SH2B adapter protein 3
O60880 SH2D1A SH2 domain-containing protein 1A
A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B
Q96LC7 SIGLEC10 Sialic acid-binding Ig-like lectin 10
O43699 SIGLEC6 Sialic acid-binding Ig-like lectin 6
Q9Y286 SIGLEC7 Sialic acid-binding Ig-like lectin 7
Q9NYZ4 SIGLEC8 Sialic acid-binding Ig-like lectin 8
Q9Y336 SIGLEC9 Sialic acid-binding Ig-like lectin 9
Q9H173 SIL1 Nucleotide exchange factor SIL1
Q96FS4 SIPA1 Signal-induced proliferation-associated protein 1
Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1
Q8IXJ6 SIRT2 NAD-dependent protein deacetylase sirtuin-2
Q9Y3P8 SIT1 Signaling threshold-regulating transmembrane adapter 1
Q86WV1 SKAP1 Src kinase-associated phosphoprotein 1
Q9H6Q3 SLA2 Src-like-adapter 2
Q9NQ25 SLAMF7 SLAM family member 7
Q9P0V8 SLAMF8 SLAM family member 8
P53985 SLC16A1 Monocarboxylate transporter 1
O94813 SLIT2 Slit homolog 2 protein
Q96PX8 SLITRK1 SLIT and NTRK-like protein 1
Q9H156 SLITRK2 SLIT and NTRK-like protein 2
Q9H5Y7 SLITRK6 SLIT and NTRK-like protein 6
Q14BN4 SLMAP Sarcolemmal membrane-associated protein
Q15797 SMAD1 Mothers against decapentaplegic homolog 1
P84022 SMAD3 Mothers against decapentaplegic homolog 3
Q99717 SMAD5 Mothers against decapentaplegic homolog 5
P51532 SMARCA4 Transcription activator BRG1
P17405 SMPD1 Sphingomyelin phosphodiesterase
Q9HCE7 SMURF1 E3 ubiquitin-protein ligase SMURF1
P60880 SNAP25 Synaptosomal-associated protein 25
O76070 SNCG Gamma-synuclein
Q8TER0 SNED1 Sushi
Q8TEQ0 SNX29 Sorting nexin-29
Q9Y5X3 SNX5 Sorting nexin-5
Q8IUW3 SPATA2L Spermatogenesis-associated protein 2-like protein
Q6UWN8 SPINK6 Serine protease inhibitor Kazal-type 6
Q08629 SPOCK1 Testican-1
Q9UBC9 SPRR3 Small proline-rich protein 3
O43597 SPRY2 Protein sprouty homolog 2
O15020 SPTBN2 Spectrin beta chain
P37108 SRP14 Signal recognition particle 14 kDa protein
P78362 SRPK2 SRSF protein kinase 2
P05455 SSB Lupus La protein
Q11201 ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2
O95630 STAMBP STAM-binding protein
P52630 STAT2 Signal transducer and activator of transcription 2
Q15831 STK11 Serine/threonine-protein kinase STK11
Q12846 STX4 Syntaxin-4
Q13190 STX5 Syntaxin-5
O15400 STX7 Syntaxin-7
Q9UNK0 STX8 Syntaxin-8
O00186 STXBP3 Syntaxin-binding protein 3
Q06520 SULT2A1 Bile salt sulfotransferase
Q5VX71 SUSD4 Sushi domain-containing protein 4
Q9UH65 SWAP70 Switch-associated protein 70
P21579 SYT1 Synaptotagmin-1
Q9NYJ8 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
P09758 TACSTD2 Tumor-associated calcium signal transducer 2
Q7Z5A7 TAFA5 Chemokine-like protein TAFA-5
Q15633 TARBP2 RISC-loading complex subunit TARBP2
Q86VP1 TAX1BP1 Tax1-binding protein 1
O14776 TCERG1 Transcription elongation regulator 1
P56279 TCL1A T-cell leukemia/lymphoma protein 1A
P13385 TDGF1 Teratocarcinoma-derived growth factor 1
P01266 TG Thyroglobulin
P01135 TGFA Protransforming growth factor alpha
P01137 TGFB1 Transforming growth factor beta-1 proprotein
P36897 TGFBR1 TGF-beta receptor type-1
P40225 THPO Thrombopoietin
Q9NQ88 TIGAR Fructose-2
P16035 TIMP2 Metalloproteinase inhibitor 2
P04183 TK1 Thymidine kinase
Q15399 TLR1 Toll-like receptor 1
O60603 TLR2 Toll-like receptor 2
O15455 TLR3 Toll-like receptor 3
O00206 TLR4 Toll-like receptor 4
Q96A25 TMEM106A Transmembrane protein 106A
Q86YD3 TMEM25 Transmembrane protein 25
O60235 TMPRSS11D Transmembrane protease serine 11D
P98073 TMPRSS15 Enteropeptidase
Q9H3S3 TMPRSS5 Transmembrane protease serine 5
P01375 TNF Tumor necrosis factor
P98066 TNFAIP6 Tumor necrosis factor-inducible gene 6 protein
O95379 TNFAIP8 Tumor necrosis factor alpha-induced protein 8
O00220 TNFRSF10A Tumor necrosis factor receptor superfamily member 10A
O14763 TNFRSF10B Tumor necrosis factor receptor superfamily member 10B
Q9Y6Q6 TNFRSF11A Tumor necrosis factor receptor superfamily member 11A
Q96RJ3 TNFRSF13C Tumor necrosis factor receptor superfamily member 13C
Q9NS68 TNFRSF19 Tumor necrosis factor receptor superfamily member 19
O95407 TNFRSF6B Tumor necrosis factor receptor superfamily member 6B
Q07011 TNFRSF9 Tumor necrosis factor receptor superfamily member 9
O14788 TNFSF11 Tumor necrosis factor ligand superfamily member 11
O43508 TNFSF12 Tumor necrosis factor ligand superfamily member 12
O75888 TNFSF13 Tumor necrosis factor ligand superfamily member 13
O43557 TNFSF14 Tumor necrosis factor ligand superfamily member 14
O95150 TNFSF15 Tumor necrosis factor ligand superfamily member 15
Q15025 TNIP1 TNFAIP3-interacting protein 1
Q92752 TNR Tenascin-R
Q02880 TOP2B DNA topoisomerase 2-beta
P04637 TP53 Cellular tumor antigen p53
Q12888 TP53BP1 TP53-binding protein 1
P51580 TPMT Thiopurine S-methyltransferase
P12270 TPR Nucleoprotein TPR
Q15661 TPSAB1 Tryptase alpha/beta-1
O43715 TRIAP1 TP53-regulated inhibitor of apoptosis 1
P19474 TRIM21 E3 ubiquitin-protein ligase TRIM21
Q14258 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25
Q6P9F5 TRIM40 E3 ubiquitin ligase TRIM40
Q9C035 TRIM5 Tripartite motif-containing protein 5
Q8NG06 TRIM58 E3 ubiquitin-protein ligase TRIM58
Q15643 TRIP11 Thyroid receptor-interacting protein 11
Q969D9 TSLP Thymic stromal lymphopoietin
P40222 TXLNA Alpha-taxilin
P04818 TYMS Thymidylate synthase
P62987 UBA52 Ubiquitin-60S ribosomal protein L40
Q9BSL1 UBAC1 Ubiquitin-associated domain-containing protein 1
P63146 UBE2B Ubiquitin-conjugating enzyme E2 B
Q9H832 UBE2Z Ubiquitin-conjugating enzyme E2 Z
P11441 UBL4A Ubiquitin-like protein 4A
P13051 UNG Uracil-DNA glycosylase
O60763 USO1 General vesicular transport factor p115
P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8
Q9BV40 VAMP8 Vesicle-associated membrane protein 8
Q9UKW4 VAV3 Guanine nucleotide exchange factor VAV3
P49765 VEGFB Vascular endothelial growth factor B
O43915 VEGFD Vascular endothelial growth factor D
O15240 VGF Neurosecretory protein VGF
O95498 VNN2 Vascular non-inflammatory molecule 2
Q86VR7 VSIG10L V-set and immunoglobulin domain-containing protein 10-like
P62760 VSNL1 Visinin-like protein 1
Q6PCB0 VWA1 von Willebrand factor A domain-containing protein 1
Q2TAL6 VWC2 Brorin
P42768 WAS Wiskott-Aldrich syndrome protein
Q9UPY6 WASF3 Wiskott-Aldrich syndrome protein family member 3
O00401 WASL Neural Wiskott-Aldrich syndrome protein
A4D1P6 WDR91 WD repeat-containing protein 91
Q9Y5W5 WIF1 Wnt inhibitory factor 1
O14904 WNT9A Protein Wnt-9a
O00308 WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2
P47992 XCL1 Lymphotactin
P98170 XIAP E3 ubiquitin-protein ligase XIAP
P07947 YES1 Tyrosine-protein kinase Yes
Q5VVQ6 YOD1 Ubiquitin thioesterase OTU1
Q9H171 ZBP1 Z-DNA-binding protein 1
Q05516 ZBTB16 Zinc finger and BTB domain-containing protein 16
Q13105 ZBTB17 Zinc finger and BTB domain-containing protein 17
Q5D1E8 ZC3H12A Endoribonuclease ZC3H12A
Q7Z7L7 ZER1 Protein zer-1 homolog
Q8WV99 ZFAND2B AN1-type zinc finger protein 2B
Q99731 CCL19 C-C motif chemokine 19
P13500 CCL2 C-C motif chemokine 2
P55773 CCL23 C-C motif chemokine 23
P20138 CD33 Myeloid cell surface antigen CD33
Q99895 CTRC Chymotrypsin-C
O14625 CXCL11 C-X-C motif chemokine 11
Q14116 IL18 Interleukin-18
P35968 KDR Vascular endothelial growth factor receptor 2
P06858 LPL Lipoprotein lipase
O00300 TNFRSF11B Tumor necrosis factor receptor superfamily member 11B
O14836 TNFRSF13B Tumor necrosis factor receptor superfamily member 13B
P15692 VEGFA Vascular endothelial growth factor A

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